A Guardian investigation into the U.S. overdose slowdown found that national declines masked sharp local disparities. Here's how the reporting team got the story.

Fast online registration saves time and boosts access, but it also brings security and compliance risks. Learn how platforms balance speed and user protection ...

Jacob Murphy says Newcastle will relish whoever they face in the Champions League last 16 after progressing via the play-offs ...

Objective To assess whether post-authorisation studies registered with the European Medicines Agency (EMA) adhere to legislation and recommendations to publicly post study protocols and results.

No doubt, you're all keen for an update on the Sandsloot underground project, not only because it's genuinely exciting, but because it has the potential to truly move the needle, and here’s why this ...