The new post reflects Buterin’s renewed focus on scaling Ethereum’s base layer, after several years in which much of the ecosystem’s scaling strategy centered on layer-2 rollups.

Late in 2025, we covered the development of an AI system called Evo that was trained on massive numbers of bacterial genomes. So many that, when prompted with sequences from a cluster of related genes ...

Don’t start with moon shots. by Thomas H. Davenport and Rajeev Ronanki In 2013, the MD Anderson Cancer Center launched a “moon shot” project: diagnose and recommend treatment plans for certain forms ...