Researchers at Karolinska Institutet have developed a rapid and cost-efficient sequencing method that can identify antibiotic ...

Proteins, one of the smallest building blocks of life on Earth, hold promise for answering some of biology's biggest ...

In a single experiment, scientists can decipher the entire genomes of many patient samples, animal models, or cultured cells.

Routine newborn screening (NBS) has transformed early disease detection. However, traditional biochemical tests limit the range of conditions that can be identified at birth. Next-generation ...

UT researchers have developed the first viable alternative to a 75-year-old method for sequencing proteins. Image of amino acids, the building blocks of proteins. Scientists at The University of Texas ...

Genetic variants that cause rare disorders may remain elusive even after expansive testing, such as exome sequencing. The diagnostic yield of genome sequencing, particularly after a negative ...

Cornell researchers have found that a new DNA sequencing technology can be used to study how transposons move within and bind to the genome. Transposons play critical roles in immune response, ...

Whole genome sequencing (WGS) is not necessarily a solution for someone with a rare, monogenic disease. Indeed, more than half of families with suspected rare monogenic diseases do not have an answer ...

What is Third-Generation Sequencing? Third-generation sequencing, also known as long-read sequencing, refers to the latest advancements in DNA sequencing technologies that enable the analysis of ...

A new study shows that long-read sequencing has the potential to improve the rate of diagnosis while reducing the time to diagnosis from years to days -- in a single test and at a much lower cost. One ...