Engineered blood vessels harness artificial intelligence (AI) and magnetoelasticity to continuously monitor blood flow and stenosis in real time.

Ovrlpy identifies overlapping cell signals in the vertical dimension of spatial transcriptomics data.

Single-cell proteomics maps protein dynamics in the developing human brain.

A model of two zinc-finger nucleases bound to DNA overlaid on an image of a metaphase chromosome spread. The side chains shown are key to the dimer interface of the cleavage domains, according to ...

Increasing access to biotech products for animal agriculture in Sub-Saharan Africa through partnerships José de la Fuente Christian Gortázar Justus Rutaisire ...

An illustration of lipid nanoparticles (green circles) targeting the lung, designed using neural networks. Witten et al. present a method (LiON) using neural networks for lipid discovery and ...

Identifying a sparse, reliable set of biomarkers from large multi-omics datasets: Hédou et al. present a machine learning framework that selects the most reliable biomarkers from large multi-omics ...

A high-definition music video is encoded and stored in DNA. Organick et al. store over 200 MB of information in DNA and develop an error-free approach to randomly access and recover individual files ...

Artwork by Pamela Goode. Neuron- and glia-like cells derived from induced pluripotent stem cells promise tractable, individualized human models of Alzheimer's, Parkinson's and amyotrophic lateral ...

Analogs of the pancreatic peptide hormone amylin are making strides in obesity as developers zoom in on oral drugs that can emulate or even improve on injectable GLP-1 agonists while avoiding muscle ...

Optimizing guide RNA design for Cas13. With data from massively parallel screens, Wessels et al. develop computational models to identify optimal guide RNAs for the RNA-targeting CRISPR enzyme Cas13d.

Artist’s impression of a protein translocating through a nanopore. Yu et al. identify conditions that allow complete proteins to translocate through a nanopore when driven by an electroosmotic effect.