Building functional human muscle in the laboratory has long been a goal of regenerative medicine, but one stubborn obstacle ...

A new 3D model shows that Duchenne gene therapy can repair muscle fibers but fails to shut down the signals that drive scarring.

Duchenne muscular dystrophy (DMD) is a neuromuscular disease causing progressive skeletal muscle weakness and fatigue. The research team led by Associate Professor Hidetoshi Sakurai (Department of ...

The mechanism of skeletal muscle contraction is a process that relies on calcium signaling. However, the physiological role of calcium-induced calcium release (CICR) through the ryanodine receptor ...

As we age, the muscles we rely on for daily activities tend to become less reliable. With enough decline, even normal movements such as getting out of bed become risky. Low muscle mass in the ...

Swallowing is a fundamental human function that supports nutrition and communication. Damage to swallowing muscles can reduce quality of life and even lead to aspiration pneumonia or malnutrition.