Hypertrophic scarring affects a large proportion of patients following burns, trauma, or surgery and arises from prolonged fibroblast hyperactivity and excessive extracellular matrix accumulation.

Christopher H. Contag explores how tissue regeneration involves organized interactions beyond just cell replacement, highlighting two emerging technologies ...

Researchers at the Centro Nacional de Investigaciones Cardiovasculares (CNIC) have discovered a specialized population of neutrophils in the skin that produce extracellular matrix components, helping ...

Scientists have engineered a lab-on-a-chip system capable of applying precisely controlled mechanical forces to biological materials that mimic the extracellular matrix.

A new study reveals that human cells, including cancer cells, possess the ability to sense their environment far beyond their immediate point of contact, potentially influencing cell movement and ...

Macrophages are central to mechanobiology research: their physical characteristics-stiffness, adhesion, and ECM (extracellular matrix) sensing-are inextricably linked to their phenotypic polarization ...

A new study, led by Prof. Liu from the department of pharmacy, University of Electronic Science and Technology of China, discovered that the extracellular cell matrix (ECM) could induce the drug ...

Within tissues, cells are embedded in complex, three-dimensional structures known as the extracellular matrix. Their biomechanical interactions play a crucial role in numerous biological processes.